Procedures for Ethics Review of Animal Use Protocols

All proposed use of animals for research, teaching, testing and display must receive ethical review, and be approved by the UACC, before the animals are obtained and the work initiated. Requests to use animals must be submitted on the Animal Use Protocol (AUP) Research or Teaching Application Form.

Ethical review of animal use protocols is conducted by the UACC Animal Research Ethics Board (AREB).

If any assistance is required with a new or renewal AUP, please contact uacc.office@usask.ca or 306-966-4126. RSEO Staff will be happy to assist by meeting in person to discuss an AUP, or providing answers via email or phone.

Submission Deadline Dates and Animal REB Meeting Dates

To accommodate regulatory requirements and to meet the needs of researchers, the AREB holds one full-board meeting per month. The AREB meets on the last Wednesday of every month, except for the December meeting, or if otherwise announced.

Deadline for receipt of new protocols in the Research Services and Ethics Office for review that month is ~4 weeks prior to the AREB meeting day according to the schedule listed below. Protocol submissions must be submitted by 4:30 pm on the submission date. Late applications will be held over to the next meeting date. Protocols will be numbered as the Research Services and Ethics Office receives them.

Amendments, revisions and updated annual approval requests that require full board approval must be submitted as per the submission date schedule to be included on the agenda of the scheduled meeting.

  • Submit completed AUP electronically by e-mail to uacc.office@usask.ca
  • Note: Signed signature page may be submitted as hard copy to UACC AREB c/o Research Services and Ethics Office, 223 - 110 Science Place, Thorvaldson Building

Animal Research Ethics Board (AREB) Schedule for 2018

SUBMISSION DATE - PROTOCOLS
MUST BE SUBMITTED BY 11:59 p.m.

FULL ANIMAL REB MEETING DATE

 Monday January 8, 2018

Wednesday January 31, 2018 (AREB-2)

Monday January 22, 2018

Wednesday February 14, 2018 (AREB-1)

 Monday February 5, 2018

Wednesday February 28, 2018 (AREB-2)

 Monday February 19, 2018

Wednesday March 14, 2018 (AREB-1)

Monday March 5, 2018

Wednesday March 28, 2018 (AREB-2)

Monday March 19, 2018

Wednesday April 11, 2018 (AREB-1)

Monday April 2, 2018

Wednesday April 25, 2018 (AREB-2)

Monday April 23, 2018

Wednesday May 16, 2018 (AREB-1)

Monday May 7, 2018

Wednesday May 30, 2018 (AREB-2)

Monday May 21, 2018

Wednesday June 13, 2018 (AREB-1)

Monday June 4, 2018

Wednesday June 27, 2018 (AREB-2)

July - No meeting

July - No meeting

Monday July 23, 2018

Wednesday August 15, 2018 (AREB-1)

Monday August 6, 2018

Wednesday August 29, 2018 (AREB-2)

Monday August 20, 2018

Wednesday September 12, 2018 (AREB-1)

Monday September 3, 2018

Wednesday September 26, 2018 (AREB-2)

Monday September 24, 2018

Wednesday October 17, 2018 (AREB-1)

Monday October 8, 2018

Wednesday October 31, 2018 (AREB-2)

Monday October 22, 2018

Wednesday November 14, 2018 (AREB-1)

Monday November 5, 2018

Wednesday November 28, 2018 (AREB-2)

Monday November 26, 2018

Wednesday December 19, 2018 (AREB-1)

Annual Review of Ongoing Protocols

Ethics approval of animal-based research protocols is issued for one year at a time, in compliance with the CCAC guidelines and the UACC Terms of Reference. 
If the research project continues beyond one year, the principal investigator must submit a completed "Annual Review Report" form to the Research Services and Ethics Office prior to the one-year anniversary approval date. A reminder of the upcoming annual review will be sent to the principal investigator within two months prior to the anniversary approval date. If the Annual Review Report form is not received by the anniversary approval date, the Research Services and Ethics Office will send a second reminder to the principal investigator indicating that the study will be closed one month after the anniversary date. If the Annual Review Report form is not received within one month of the second reminder, the protocol will be considered "completed".

Protocol Modifications

During the course of the year (prior to the annual review), if any changes are required (e.g. different species or strain, increase in numbers of animals, change in animal procedures) these modifications must first be approved by the UACC AREB, before the changes can be incorporated into the research program. Modification requests must be submitted on the Animal Use Protocol (AUP) Modification Form.

Acknowledgement of Ethics Review

The UACC requires that the following statement of acknowledgement to indicate research has been reviewed and approved by the UACC AREB be encouraged on all posters and publications by researchers and students. It is also important for researchers and students to understand the time and commitment that the volunteer members of the AREB provide to the UACC.

This work was approved by the University of Saskatchewan’s Animal Research Ethics Board and adhered to the Canadian Council on Animal Care guidelines for humane animal use.

Scientific Peer Review of Animal Use Protocols

According to the CCAC policy statement on: the importance of independent peer review of the scientific merit of animal-based research projects, it is the institution’s responsibility to have in place a mechanism to ensure that proposed animal use for research is independently peer-reviewed for its scientific merit before it is given final approval by the University Animal Care Committee (UACC) Animal Research Ethics Board (AREB).

All proposed animal-based research work must be peer reviewed for scientific merit, at arm's length from the UACC AREB. The AREB will not not issues a Certificate of Approval for a new or 4-year renewal animal use protocol if confirmation that scientific merit has been demonstrated through an independent peer review is not demonstrated to the AREB.

The Research Services and Ethics Office has compiled a list of funding agencies that are known to conduct peer review as part of their granting process. The Office of Vice-President Research Scientific Merit Review Committee for Animal Use Protocols (SMRC) is responsible for ensuring that all proposed animal-based work has received peer review for scientific merit. Please refer to the Scientific Peer Review Assessment Form for Evaluation of Scientific Merit relating to Animal Use Protocols for guidance as to the questions asked during the peer review process and refer to the Procedure for Scientific Merit Review of Animal Use Protocols (Principal Investigators).

The Three Rs (Replacement, Reducation and Refinement)

The CCAC Three Rs microsite is a unique Canadian resource that includes information on Replacement, Reduction and Refinement in research, testing and teaching. In addition, the Three Rs Search Guide is a resource designed to facilitate investigators to consider the Three Rs during animal use protocol preparation.

The Three Rs microsite contains other useful tools such as: The Animal Index (grouping Three Rs resources by category and/or species to assist in finding resources specific to certain types of animals) and Care & Techniques(information about refinements to animal care and animal-based scientific techniques).

The National Centre for the Replacement, Refinement & Reduction of Animals in Research (NC3Rs) ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines are intended to improve the reporting of research using animals – maximising information published and minimising unnecessary studies. First published in 2010, the ARRIVE guidelines are endorsed by a growing list of journals, funders, and academic institutions. Refer to the ARRIVE guidelines and ARRIVE guidelines checklist as an aid to project planning and experimental design considerations. NOTE - Animal Research Ethics Board (AREB) review of an Animal Use Protocol will consider ARRIVE guidelines checklist items and recommendations as appropriate.